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Hemophilic pseudotumor-is there a role of radiotherapy? A case report with review of literature
Hemophilic pseudotumors are a rare but serious complication. They are more common in the weight-bearingjoints. These lesions could be treated by conservative measures using factor VIII cryoprecipitate or by radiationtherapy as an alternative to surgery with good results. We present a case of chronic hemophilia withpseudotumor of the right knee joint who was treated with low dose external beam radiation with fair results.

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Authors: Rakesh Kapoor, Jayant Sastrı, Pankaj Malhotra, Vinay Kumar, Paramjit Sıngh

Keywords:

  • Year: 2006
  • Number: 1
  • Referance No: 03274

  • Figure 1. X-ray of the right leg and knee joint showing lytic expansile lesion of the tibia and the fibula with fracture of medial cortex of the tibia with extensive periosteal reactions, soft tissue calcifications and prominent coarse trabeculations.
  • Figure 2. Simulation X-ray shows the target volume consisting of proximal tibia/fibula, the knee joint and distal femur.
  • Figure 3. Pre-radiotherapy sagittal T1 spin echo and flash T2-weighted MRI images showing expansile hyperintense lesion in the proximal epiphyseal region of the right tibia with heterogenous signal intensity on both T1- and T2- weighted images with a concentric layered appearance, suggestive of presence of blood degeneration products as well as thrombus.
  • Figure 4. Post-radiotherapy, MRI showing minimal reduction in the size of the lesion with some alteration in signal intensity due to evolution of the hemorrhagic products.

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